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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SP2 All Species: 10.61
Human Site: S170 Identified Species: 25.93
UniProt: Q02086 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q02086 NP_003101.3 613 64900 S170 N Q A I I T P S P S S H K P V
Chimpanzee Pan troglodytes XP_511930 613 64912 S170 N Q A I I T P S P S S H K P V
Rhesus Macaque Macaca mulatta XP_001083602 613 64841 S170 N Q A I I T P S P S S H K P V
Dog Lupus familis XP_539462 788 82259 A271 N I G G V T L A L P V I N N V
Cat Felis silvestris
Mouse Mus musculus Q9D2H6 612 64890 T170 Q A I T T P S T S G H K P V P
Rat Rattus norvegicus Q01714 786 80753 R219 N Q Q I I T N R G S G G N I I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514802 816 85651 P243 S G Q I Q I L P G S N Q G V L
Chicken Gallus gallus Q90WR8 771 80932 P199 T G Q I Q I I P G S N Q T I I
Frog Xenopus laevis NP_001090151 560 59558 N153 A L L A P T T N T S K H V P I
Zebra Danio Brachydanio rerio NP_001093452 608 64535 T170 T V Q A A T P T A P P L A P A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 99.6 33.5 N.A. 93.8 29.2 N.A. 27.9 28.9 60.6 60.5 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.8 100 45.5 N.A. 95.7 41.7 N.A. 41.4 42.2 72.7 71.1 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 20 N.A. 0 40 N.A. 13.3 13.3 26.6 20 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 33.3 N.A. 6.6 46.6 N.A. 33.3 26.6 40 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 30 20 10 0 0 10 10 0 0 0 10 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 20 10 10 0 0 0 0 30 10 10 10 10 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 10 40 0 0 0 % H
% Ile: 0 10 10 60 40 20 10 0 0 0 0 10 0 20 30 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 10 10 30 0 0 % K
% Leu: 0 10 10 0 0 0 20 0 10 0 0 10 0 0 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 50 0 0 0 0 0 10 10 0 0 20 0 20 10 0 % N
% Pro: 0 0 0 0 10 10 40 20 30 20 10 0 10 50 10 % P
% Gln: 10 40 40 0 20 0 0 0 0 0 0 20 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % R
% Ser: 10 0 0 0 0 0 10 30 10 70 30 0 0 0 0 % S
% Thr: 20 0 0 10 10 70 10 20 10 0 0 0 10 0 0 % T
% Val: 0 10 0 0 10 0 0 0 0 0 10 0 10 20 40 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _